Gross phenotype of cilia-related mutants and wild-type (WT) zebrafish across time. Lateral views of WT and mutant animals at 2 days post fertilization (dpf), 5 dpf, 3 weeks post fertilization (wpf) and >3 months post fertilization (mpf; adult). The penetrance of the imaged phenotype [curled-down tail (CDT) and/or scoliosis for most, a decreased head-trunk-angled defect (HTA) for mks1 and b9d2, and small size for tmem216] in −/− animals is indicated in the bottom right of each panel (P, observed/total number of −/− identified). At 3 wpf and in adults, we indicate the Mendelian inheritance (MI) in the bottom left of each panel. MI was calculated as % of the number of observed −/− divided by the expected number of −/− (1/3 of the sum of observed +/+ and +/−). Scale bars: 1000 μm.
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