FIGURE
Figure 2
- ID
- ZDB-FIG-221226-281
- Publication
- Ruzic et al., 2022 - Discovery of 1-Benzhydryl-Piperazine-Based HDAC Inhibitors with Anti-Breast Cancer Activity: Synthesis, Molecular Modeling, In Vitro and In Vivo Biological Evaluation
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Figure 2
Examples of selective HDAC6 inhibitors: (A) ricolinostat, (B) tubastatin A, and (C) ACY-1083, in which CAP groups are labeled in blue; (D) synthetic routes to produce final products 2b–9b starting from 1-benzhydryl piperazine (CAP group) are presented on the bottom right corner, in which n represents the number of carbon atoms in the hydrocarbon linker; (E) table with calculated SAtot and Vx descriptors for selected CAP groups and 1-benzhydryl piperazine as a template, presented in the right upper corner. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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