Fig 9
Ovaries of activin ?A female mutants at 240 dpf (A) and 300 (B) dpf. The control and inhbab single mutant fish showed normal ovarian morphology and structure whereas the inhbaa mutant showed severe ovarian disorganization and dysfunction. Much of the space in the inhbaa-/- ovary was occupied by stromal cells and fibrous tissues (asterisk). The boxed areas are shown at higher magnification below. The numbers shown in the photos indicate the total number of fish examined (lower) and the fish exhibiting similar phenotype to that shown (upper). PG, primary growth; PV, pre-vitellogenic; FG, full-grown. |