FIGURE

Fig. 6

ID

ZDB-FIG-221101-24

Publication

Kugler et al., 2021 - The effect of absent blood flow on the zebrafish cerebral and trunk vasculature

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Fig. 6

Cell death is increased by absent blood flow. (A, B and C) Cell death, visualized in the transgenic reporter line Tg(secAnnexinV:mVenus)^SH632 (n = 13–15; three experimental repeats; 3dpf). (D, E and F) Annexin levels in the trunk vasculature appeared visually similar between groups. (G) Quantification of cerebral annexin SNR showed an increase in tnnt2a MO in comparison to uninjected controls (P = 0.0012) but not control MO (P = 0.072; Kruskal–Wallis test). (H) Quantification of trunk annexin SNR showed no increase in tnnt2a MO in comparison to uninjected controls (P > 0.9999) or control MO (P > 0.9999; Kruskal–Wallis test). (I) Quantification of cerebral annexin foci (white arrowheads) showed no increase in tnnt2a MO in comparison to uninjected controls (P > 0.9999) and control MO (P = 0.4542; Kruskal–Wallis test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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