FIGURE

Figure 4

ID

ZDB-FIG-221029-74

Publication

Haynes et al., 2022 - KLC4 shapes axon arbors during development and mediates adult behavior

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Figure 4

Axon orientation profiling reveals increased posterior directionality of peripheral axons in klc4^uw314 mutants.

(A–B) A representative region of axon analysis for a 24 hpf wild type (A) and klc4^uw314 (B) embryo. The axons are color coded for directionality according to the legend in the upper left corner of (A). (C) Plot of axon directionality in 24 hpf wild type (green) and klc4^uw314 mutants (magenta). (D) Axon directionality data was normalized to total signal and posterior angles are displayed to compare directional bias. Area under the curve was measured for shaded area and tested for statistical significance using a t-test. **P=0.0047. For (C–D), error bars = 95% CI. Wild type N=40 embryos, klc4^uw314 N=23 embryos.

Expression Data

Gene:	GFP
Fish:	uw4Tg (AB/TL) klc4^uw314/uw314; uw4Tg (AB)
Anatomical Term:	Rohon-Beard neuron axon
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	klc4^uw314/uw314; uw4Tg (AB)
Observed In:	Rohon-Beard neuron axonal growth cone
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Figure 4

Figure 4

Axon orientation profiling reveals increased posterior directionality of peripheral axons in klc4uw314 mutants.

Axon orientation profiling reveals increased posterior directionality of peripheral axons in klc4^uw314 mutants.