FIGURE

Fig. 3

ID

ZDB-FIG-220921-125

Publication

Andreassen et al., 2022 - Brain dysfunction during warming is linked to oxygen limitation in larval zebrafish

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Fig. 3

CT_max precedes the brain-wide depolarization in freely swimming zebrafish larvae. (A) Schematic overview of the experimental setup for calcium imaging in freely swimming, 5-d-old Tg(elavl3:GCaMP6s) zebrafish larvae. (B) Top view of setup with color-coded time projection of a heat-ramp fish’s movements in the setup for 3 min (34 to 35 °C). (C) Representative images of brain fluorescence in the same fish as in B, before (Left) and during (Right) the brain-wide depolarization. (D) CT_max and depolarization-onset temperatures measured in heat-ramp fish (black circles; n = 7) (SI Appendix, Table S5). The bars and error bars indicate the mean and SE.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA