FIGURE

Fig. 5

ID
ZDB-FIG-220921-116
Publication
Lou et al., 2022 - Mafba and Mafbb regulate microglial colonization of zebrafish brain via controlling chemotaxis receptor expression
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Fig. 5

Macrophages in DMut do not respond to lysoPS. (A) Schematic diagram indicates the PBS/lysoPS injection region. (B) Representative images of recruited macrophages in the optic tectum (OT) region in PBS/lysoPS-injected siblings, mafba mutants, mafbb mutants, and DMut embryos in Tg(Xla.Tubb:bcl-2;mpeg1:DsRedx) double-transgenic background. Macrophages are labeled in red color. Dashed lines indicate the optic tectum region. Arrows represent recruited macrophages in the OT. hpi, hours post injection. (C) Quantification of recruited macrophage number in the OT region in PBS/lysoPS-injected siblings (n = 9 for PBS or 15 for lysoPS), mafba mutants (n = 8 for PBS or 18 for lysoPS), mafbb mutants (n = 5 for PBS or 21 for lysoPS), and DMut embryos (n = 9 for PBS or 18 for lysoPS) in Tg(Xla.Tubb:bcl-2;mpeg1:DsRedx) double-transgenic background (mean ± SD; two-way ANOVA; nonsignificant [ns] P > 0.05, *P < 0.05, **P < 0.01, ****P < 0.0001).
Expression Data
Gene:
Fish:
Condition:
Anatomical Term:
Stage: Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA
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