FIGURE

Figure 6.

ID

ZDB-FIG-220912-59

Publication

Ivica et al., 2022 - Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor

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Figure 6.

Comparison of the ECD-TMD interface in different agonist-bound complexes.

(A) Superposition of the ECD-TMD interface of the open states of the glycine (salmon), taurine (green), or AMS (blue) bound forms. The key amino acids at the ECD-TMD interface are shown in stick representation. Key secondary structure elements are labelled. The blue spheres represent the centers of mass of the secondary structure elements for the AMS-bound structure. (B) Schematic diagram illustrating the distances (�) of the center of mass points shown in panel (A) of glycine-, taurine-, and AMS-bound open states. ECD, extracellular domain; TMD, transmembrane domain.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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