FIGURE

Figure 4.

ID
ZDB-FIG-220912-56
Publication
Ivica et al., 2022 - Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor
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Figure 4.

Comparison of ion channel pores.

(A, B) Shape and ion permeation pathway for AMS-bound desensitized (see also (C)) and open (see also (D)) states. M2 helices and key amino acids are shown in ribbon and stick representation, respectively. Purple, green, and red spheres define radii >3.5 Å, 1.8?3.5 Å, and <1.8 Å. (C, D) Profiles of pore radii calculated by the HOLE program for desensitized (A) and open (B) states bound with AMS, taurine, and glycine. The C? position of R268 was set to 0. AMS, aminomethanesulfonic acid.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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