FIGURE

Figure 3

ID

ZDB-FIG-220912-52

Publication

Ivica et al., 2022 - Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor

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Figure 3

Cryo-EM analysis of structures of zebrafish α1 GlyR bound to AMS.

(A–C) Cryo-EM density maps for desensitized, open, and expanded-open states with one subunit highlighted. The AMS density is in red. (D–F) Atomic models for desensitized, open, and expanded-open states. Shown are GlyR in cartoon representation, AMS in sphere representation (red), and N-glycans in stick representation. AMS, aminomethanesulfonic acid; EM, electron microscopy.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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