ZFIN Image: Ivica et al., 2022, Figure 4.

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Figure Caption

Figure 4.

Comparison of ion channel pores.

(A, B) Shape and ion permeation pathway for AMS-bound desensitized (see also (C)) and open (see also (D)) states. M2 helices and key amino acids are shown in ribbon and stick representation, respectively. Purple, green, and red spheres define radii >3.5 �, 1.8?3.5 �, and <1.8 �. (C, D) Profiles of pore radii calculated by the HOLE program for desensitized (A) and open (B) states bound with AMS, taurine, and glycine. The C? position of R268 was set to 0. AMS, aminomethanesulfonic acid.

Acknowledgments

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