FIGURE

Fig. 7

ID
ZDB-FIG-220212-7
Publication
Höijer et al., 2022 - CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations
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Fig. 7

Examples of large SVs at on-target sites in individual juvenile F1 zebrafish, a 1053 bp deletion in sh2b3 (a) and a 292 bp insertion in ywhaqa (b). c, d The same variants are observed in pools of F1 larvae from the same F0 pair as the individuals in (a) and (b). The plots show the number of reads with the large SV and the reads without the variant (i.e., unmodified and other Cas9-induced variants). The Cas9 cleavage sites are indicated by the dashed red lines.

Expression Data

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Antibody Labeling
No data available
Phenotype Data

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Acknowledgments
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