FIGURE

Fig. 3

ID

ZDB-FIG-220212-3

Publication

Höijer et al., 2022 - CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations

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Fig. 3

a On-target CRISPR-Cas9 editing efficiencies in pools of founder larvae for the four gRNAs ldlra, nbeal2, sh2b3, and ywhaqa. Each circle corresponds to the editing efficiency in a specific larvae pool, and the average values are indicated by solid circles. b Off-target CRISPR-Cas9 editing efficiencies in pools of founder larvae. c, d Line graphs visualizing the CRISPR-Cas9 editing efficiencies at on- and off-target sites in individual adult founders. Each colored line shows the editing efficiencies at the on- and off-target site(s) in one individual. Source data are provided as a Source Data file.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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