FIGURE

Figure 1

ID
ZDB-FIG-220131-657
Publication
Leask et al., 2021 - Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish
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Figure 1

AFN causes craniofacial defects which are rescued by RBC. (A) Representative images of larvae at 5 dpf (lateral view) with normal cartilage (top left) and abnormal cartilage; mild (top right), gaped jaw (bottom left) and severe (bottom right) as a result of 5 μM AFN treatment. (B) Proportion of larvae with normal craniofacial cartilage in untreated controls, RBC (500 µM) exposure 6 hpf–5 dpf, RBC (500 µM) exposure 1–5 dpf, 5 µM AFN only, 5 µM AFN with concurrent exposure to RBC (500 µM) starting at 6 hpf through to 5 dpf, 5 µM AFN with separate exposure to RBC (500 µM) with RBC treatment commencing at 1 dpf through to 5 dpf. Error bars show the standard error of the mean from three biological replicates. Data labels show the total number of larvae observed for each treatment group. Auranofin, AFN; Riboceine, RBC; hours post fertilization, hpf; days post fertilization, dpf.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxidants (Basel)