Figure 4
- ID
- ZDB-FIG-220131-607
- Publication
- Leask et al., 2021 - Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish
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RBC treatment alters AFN-induced antioxidant gene expression response. The normalized expression levels of gclc; (A) gstp1; (B) and prdx1; (C) from untreated controls, RBC (500 µM) exposure (6 hpf?5 dpf), 5 µM AFN at 24 hpf and 5 µM AFN with concurrent RBC exposure (starting at 6 hpf). Error bars are standard error of the mean from three biological replicates (n = 10 embryos in each replicate). Data not sharing a letter are statistically significantly different (p < 0.05) as assessed by one-way ANOVA, Tukey post-hoc analysis. Auranofin, AFN; Riboceine, RBC; hours post fertilization, hpf; days post fertilization, dpf. |