FIGURE

Fig. 5

ID
ZDB-FIG-220113-15
Publication
Yang et al., 2021 - A single-cell-resolution fate map of endoderm reveals demarcation of pancreatic progenitors by cell cycle
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Fig. 5

The coordination of the cell cycle state and pancreatic fate propensity involves Shh signaling. (A) The shha mRNA but not bmpMO or the dominant-negative Bmpr rescued the reduction of pancreatic endocrine cells caused by overexpression of geminin or Cdk2. The shhaMO rescued the expansion of pancreatic endocrine cells caused by gemMO or Cdkn1c overexpression. (B) The results were confirmed by the statistics (n = 5). (Scale bar, 50 ?m.) Data are expressed as mean ± SD; P value is calculated using Student?s t test.

Expression Data
Antibodies:
Fish: (all 9)
Knockdown Reagents:
Anatomical Term:
Stage: Prim-5

Expression Detail
Antibody Labeling
Phenotype Data
Fish: (all 7)
Knockdown Reagents:
Observed In:
Stage: Prim-5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA
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