FIGURE

Figure 1

ID

ZDB-FIG-211216-88

Publication

Farr et al., 2021 - Characterization of the Immune Response to Vibrio cholerae Infection in a Natural Host Model

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Figure 1

Adaptive immune responses in zebrafish against V. cholerae infection. WT zebrafish (n=5) were infected with E7946 (El Tor) or 25493 (non-O1) strains of V. cholerae at 2.5 x 10⁷ CFU/mL and then sacrificed at the indicated time points. (A) T-bet expression in fish infected with El Tor strain E7946. (B) T-bet expression in fish infected withnon-O1 strain 25493. (C) GATA3 expression in fish infected with El Tor strain E7946. (D) GATA3 expression in fish infected with non-O1 strain 25493. T-bet and GATA3 gene expression levels in zebrafish mRNA were determined through qRT-PCR. Gene expression was normalized against β-actin and expressed as fold change. Error bars indicate standard deviation. Data shown is from three experiments. *P < 0.05 as compared to control, **P < 0.05 as compared to 24 h infection.

Expression Data

Genes:	gata3 tbx21
Fish:	AB
Condition:	bacterial treatment by exposure to environment: Vibrio cholerae
Anatomical Term:	intestine
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	bacterial treatment by exposure to environment: Vibrio cholerae
Observed In:	intestine
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Infect Microbiol