FIGURE
Fig. 6
- ID
- ZDB-FIG-211206-7
- Publication
- Jin et al., 2021 - Copper ions impair zebrafish skeletal myofibrillogenesis via epigenetic regulation
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Fig. 6
Working model for how Cu2+ induces myofibrillogenesis defects. Cu2+ overload in the embryonic cells of Cu2+-stressed embryos and larvae led to the downregulation of the smyd1b-H3K4me3 signaling axis and changed the promoter methylation level of gene smyd5. The downregulated expression of smyd1b and the up-regulated expression of smyd5 might contribute jointly to the occurrence of muscle fiber specification defects in Cu2+-stressed embryos and larvae |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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