FIGURE

Figure 5

ID

ZDB-FIG-211201-176

Publication

Chen et al., 2021 - Knockout of mafba Causes Inner-Ear Developmental Defects in Zebrafish via the Impairment of Proliferation and Differentiation of Ionocyte Progenitor Cells

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Figure 5

Increased apoptosis in the epidermal stem cells and dlc⁺ ionocyte progenitor cells of mafba^−/− zebrafish. (A) Examples of p63 with dlc, p63 with TUNEL, or dlc with TUNEL colocalized (arrowhead) or non-colocalized (arrow) cells are shown. (B) The quantitative analyses of p63⁺ cells, dlc⁻p63⁺ cells, and dlc⁺p63⁺ cells of sibling and mafba^−/− embryos at the bud stage are shown in (a). The quantitative analysis of p63⁺, dlc⁻p63^+, and dlc⁺p63⁺ cell numbers colocalized with TUNEL in sibling and mafba^−/− embryos at the bud stage are shown in (b). The n = 12 for each panel. Scale bars: 100 µm. Data are mean ± SD; ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001.

Expression Data

Antibodies:	Ab1-tp63 Ab2-dlc
Fish:	mafba^hzu17/hzu17
Anatomical Terms:	epidermal stem cell ionocyte progenitor cell keratinocyte progenitor cell
Stage:	Bud

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mafba^hzu17/hzu17
Observed In:	epidermal stem cell epidermal stem cell apoptotic process ionocyte apoptotic process ionocyte progenitor cell keratinocyte progenitor cell apoptotic process
Stage:	Bud

Phenotype Detail

Acknowledgments

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