Fig. 7
Switch from an overfeeding diet to a normal diet partially decreased body weight and BMI of DIO fish. (A) Body weight of CTRL and DIO zebrafish after 4 weeks of overfeeding. (B) BMI (g/cm2) after 4 weeks of overfeeding. (C, D) Body weight and BMI following 2 weeks of standard diet after the 4th week of overfeeding. These measurements were done at week 6 (W6: 4 weeks of overfeeding +2 weeks of normal diet). The DIO fish involved in this procedure were called “DIO Reversible” fish. n = 14–16. Error bars correspond to SEM. Student's t-test (A, B) and one-way ANOVA (C, D). *p < 0.0.5; **p < 0.01; ***p < 0.001. |