FIGURE

FIGURE 8

ID

ZDB-FIG-211106-13

Publication

Luo et al., 2021 - Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin

Other Figures

All Figure Page

Back to All Figure Page

FIGURE 8

Nxhl controls angiogenesis by targeting VE-PTP (ptprb)-related angiogenic genes. (A) Schematic model illustrating the mechanism of nxhl in zebrafish angiogenesis and heart development. The interactions between nxhl mRNA and NCL protein, NCL protein and ptprb mRNA are new-found interactions in this study. It connects with the keystone network of angiogenesis and heart development. (B) Possible mechanism of nxhl in zebrafish angiogenesis and heart development. Knockdown of nxhl may downregulate the nxhl-NCL-ptprb complex, subsequently regulate the proteins associated with angiogenesis and heart development, and finally result in heart pericardial edema, vascular patterning and integrity defects.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol