FIGURE

FIGURE 7

ID

ZDB-FIG-211106-12

Publication

Luo et al., 2021 - Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin

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FIGURE 7

Nxhl attenuates tumor invasion and proteins associated with angiogenesis and EMT. (A) Silence of nxhl (homolog of Harbi1) inhibits migration and EMT of HCC cells. Representative images of migrated cells stained with crystal violet and inhibition of migration in nxhl-siRNA treated HepG2 cell (up row). Representative images of colony formation cells stained with crystal violet and inhibition of colony forming in nxhl-siRNA treated HepG2 cell (down row). (B) Silence of nxhl inhibits epithelial-mesenchymal transition of HepG2 cells. Four EMT marker proteins, NCL, NCL T76 and VE-PTP were detected using Western blotting method in control and siRNA-treated HepG2 cells. (C) nxhl (Harbi1) expression in 72 HCC tissues and para-cancer tissues. qPCR was used to determine the human homolog of nxhl (Harbi1) expression levels. The data above represent as mean ± SEM from three independent experiments. *p < 0.05, **p < 0.001 represents statistically significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol