FIGURE

Figure 8

ID

ZDB-FIG-210707-26

Publication

Shan et al., 2021 - Identification and functional characterization of a fish-specific tlr19 in common carp (Cyprinus carpio L.) that recruits TRIF as an adaptor and induces ifn expression during the immune response

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Figure 8

Activation of ifn mediated by CcTlr19.A Luci-ifn and nf-kb reporter plasmids, rhRL-TK and CcTlr19-FUGW expression vector or an empty vector (control) were transfected into 293 T cells. After 48 h, Firefly and Renilla luciferase activities were detected, and the ratio was calculated. Means ± SD (n = 4), *P < 0.05, ***P < 0.001, ****P < 0.0001, t test. B–D 293 T cells were transfected targeted plasmid. After 36 h, the cells were stimulated with poly(I:C), PGN and LPS for the indicated periods of time. Firefly and Renilla luciferase activities were detected, and the ratio was calculated. Means ± SD (n = 4), *P < 0.05, ***P < 0.001, ****P < 0.0001, two-way ANOVA.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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