FIGURE

Figure 1

ID

ZDB-FIG-210707-18

Publication

Shan et al., 2021 - Identification and functional characterization of a fish-specific tlr19 in common carp (Cyprinus carpio L.) that recruits TRIF as an adaptor and induces ifn expression during the immune response

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Figure 1

Cloning of the full-length cDNA of Cctlr19.A A schematic diagram showing the domain architecture of common carp Tlr19. The gray box represents the signal peptide. The leucine-rich-repeat (LRR) regions are shown with green rectangles. The transmembrane (TM) domains are shown with red rectangles, and Toll/interleukin-1 receptor (TIR) domains are shown as yellow ovals. B Modeled three-dimensional structure of common carp Tlr19 shown as a cartoon. C Phylogenetic analysis of Tlr19 amino acid sequences. The phylogenetic tree was constructed using multiple alignment of amino acids generated by the neighbor-joining method in the MEGA 6.0. program. Green, black, purple, blue, red and orange color represents the TLR1, 3, 4, 5, 7 and 11 subfamilies, respectively, while the black box indicated the CcTlr19. The GenBank accession numbers of TLR sequences are shown in Additional file 1.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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