ZFIN ID: ZDB-FIG-210311-52
Badrock et al., 2020 - Analysis of U8 snoRNA Variants in Zebrafish Reveals How Bi-allelic Variants Cause Leukoencephalopathy with Calcifications and Cysts. American journal of human genetics   106(5):694-706 Full text @ Am. J. Hum. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: 14-19 somites to Long-pec
PHENOTYPE:
Fish:
Observed In:
Stage Range: 14-19 somites to Long-pec

Fig. S12 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
baxa snord118aue501/ue501 standard conditions Prim-5 whole organism RTPCR
ccng1 snord118aue501/ue501 standard conditions Prim-5 whole organism RTPCR
cdkn1a snord118aue501/ue501 standard conditions Prim-5 whole organism RTPCR
mCherry snord118aue501/ue501; ue503Tg standard conditions Long-pec lens IFL
mdm2 snord118aue501/ue501 standard conditions Prim-5 whole organism RTPCR
Venus snord118aue501/ue501; ue503Tg standard conditions 14-19 somites whole organism IFL
Prim-5 eye IFL
Prim-5 hindbrain IFL
Prim-5 somite IFL
Long-pec whole organism IFL
ue503Tg standard conditions 14-19 somites Not Detected whole organism IFL
Prim-5 Not Detected eye IFL
Prim-5 Not Detected hindbrain IFL
Prim-5 Not Detected somite IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
snord118aue501/ue501 standard conditions Prim-5 whole organism baxa expression increased amount, abnormal
Prim-5 whole organism ccng1 expression increased amount, abnormal
Prim-5 whole organism cdkn1a expression increased amount, abnormal
Prim-5 whole organism mdm2 expression increased amount, abnormal
snord118aue501/ue501; ue503Tg standard conditions 14-19 somites whole organism Venus expression increased amount, abnormal
Prim-5 eye Venus expression increased amount, abnormal
Prim-5 hindbrain Venus expression increased amount, abnormal
Prim-5 somite Venus expression increased amount, abnormal
Long-pec embryo development delayed, abnormal
Long-pec eye decreased size, abnormal
Long-pec fourth ventricle swollen, abnormal
Long-pec whole organism Venus expression increased amount, abnormal
Full text @ Am. J. Hum. Genet.