Figure 7—figure supplement 1.

MEP glia are absent along the motor root in <italic>nrg1</italic> mutant larvae.

(A) In situ hybridization showing plp1a+ oligodendrocytes in the spinal cord (outlined arrowheads) in nrg1+/+ larvae and in both the CNS (outlined arrowheads) and the PNS (arrowhead) in nrg1-/- larvae at 3 dpf. (B) Dorsal view of the zebrafish trunk showing wif1+ MEP glia in WT and nrg1-/- larvae at 3 dpf. wif1+ MEP glia are located at the edge of the spinal cord (white outlined arrowheads) in WT larvae while their location is lateral (white arrowheads), close to the skin, in nrg1-/- larvae. Yellow brackets denote the width of the spinal cord. White dashed lines denote the trunk. Scale bar, (A) 10 µm, (B) 250 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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