FIGURE

Figure 7

ID

ZDB-FIG-210206-20

Publication

Palominos et al., 2021 - The Olfactory Organ Is Populated by Neutrophils and Macrophages During Early Development

Other Figures

All Figure Page

Back to All Figure Page

Figure 7

Exposure to copper reveals distinct classes of macrophages. (A-A^‴) 5-dpf Tg(mpeg1:mCh);Tg(mpx:GFP);Tg(OMP:YFP) olfactory organ (OO) and imaging continued at times indicated (see Supplementary Video 3 for sequence taken every minute). (A) Imaging was initiated at time 0′. (A′) Larvae were exposed to 10 μM of CuSO₄ at 30′. Individual cell tracking reveals the presence of (B) fixed and (C) wandering macrophages. (D) Before copper exposure (from boxed are in A), macrophages (red) are found associated with OSNs (green) in the ventral OO. (D′) After exposure to copper (from boxed are in Figure 6A^‴), macrophages (mpeg1:mCh+, red) accumulate at the ventral–basal OO, in close association with degenerating OSNs (green, OMP:YFP+). Arrowheads indicate places where macrophages appeared to engulf degenerating OSNs (mpeg1:mCh+ and OMP:YFP+). Scale bars: A-A^‴ = 75 μm, D = 25 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol