FIGURE

Figure 3

ID

ZDB-FIG-210204-75

Publication

Dries et al., 2021 - Cell Proliferation and Collective Cell Migration During Zebrafish Lateral Line System Development Are Regulated by Ncam/Fgf-Receptor Interactions

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Figure 3

Ncam1b affects the expression of the Fgfr1a-target gene erm. Tg(ClaudinB::lynGFP) embryos were immunostained labeled for GFP (green). In situ hybridizations of probes detecting lef1 (Leading-Zone), fgfr1a, or erm (both in the Trailing-Zone) were visualized by NBT/BCIP staining. Primordia outlines are surrounded with a dotted line for better visibility. (A–C) Neither expression of lef1 nor of fgfr1a are affected in ncam1b-morphants, whereas erm expression is markedly reduced. (A′,C′) Neither ncam1a-morphants nor (A″,C″) siblings show alterations for lef1, fgfr1a, or erm. (D) Reduced erm expression after knockdown of ncam1b. Error bars show standard deviation. X²-test with ns = p ≥ 0.05. Scale bar 20 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol