FIGURE

Figure 6

ID

ZDB-FIG-210204-79

Publication

Dries et al., 2021 - Cell Proliferation and Collective Cell Migration During Zebrafish Lateral Line System Development Are Regulated by Ncam/Fgf-Receptor Interactions

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Figure 6

Expression of chemokine receptor cxcr7b is affected by knockdown of ncam1b. Tg(ClaudinB::lynGFP) embryos (48 hpf) were immunostained for GFP (green). In situ hybridizations of probes detecting cxcr4b (complete PrimI) and cxcr7b (Trailing-Zone), were visualized by NBT/BCIP staining. Primordia outlines were surrounded with a dotted line for better visibility. (A,A′) Expression of cxcr4b is not affected in ncam1b-morphants, whereas expression of cxcr7b is markedly reduced. (B,B′) In ncam1a-morphants cxcr7b is present, whereas cxcr4b expression is reduced. (C,C′) In siblings, cxcr7b is robustly expressed in the Trailing-Zone. (D) Drastically reduced cxcr7b expression after knockdown of ncam1b. Error bars represent standard deviation. X²-test with ns = p ≥ 0.05. Scale bar 20 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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