ZFIN ID: ZDB-FIG-201124-9
Del Dotto et al., 2019 - SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder. The Journal of Clinical Investigation   130(1):108-125 Full text @ Journal of Clin. Invest.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Long-pec to Days 14-20
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Long-pec to Days 14-20

Fig. S6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP cms1Tg control Days 14-20 lens mitochondrion IFL
cms1Tg + CRISPR1-ssbp1 standard conditions Days 14-20 lens mitochondrion IFL
mt-co1 WT control Long-pec whole organism RTPCR
WT + CRISPR1-ssbp1 standard conditions Long-pec whole organism RTPCR
mt-nd1 WT control Long-pec whole organism RTPCR
WT + CRISPR1-ssbp1 standard conditions Long-pec whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + CRISPR1-ssbp1 standard conditions Long-pec cranial nerve II size, normal
Long-pec whole organism morphology, normal
cms1Tg + CRISPR1-ssbp1 standard conditions Days 14-20 lens mitochondrion decreased amount, abnormal
Days 14-20 lens mitochondrion EGFP expression decreased amount, abnormal
Full text @ Journal of Clin. Invest.