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Gene

mt-nd1

ID
ZDB-GENE-011205-7
Name
NADH dehydrogenase 1, mitochondrial
Symbol
mt-nd1 Nomenclature History
Previous Names
  • mtnd1 (1)
  • ND1 (1)
Type
protein_coding_gene
Location
Chr: MT Mapping Details/Browsers
Description
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in female organism. Human ortholog(s) of this gene implicated in several diseases, including MELAS syndrome; neurodegenerative disease (multiple); optic nerve disease (multiple); toxic shock syndrome; and type 2 diabetes mellitus. Orthologous to human MT-ND1 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mt-nd1 Human Ortholog
No data available
Associated With mt-nd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site
Family IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H
Domain Details Per Protein
Protein Length NADH:ubiquinone oxidoreductase, subunit 1, conserved site NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H
UniProtKB:Q9MIZ0 324
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations