Figure 4
- ID
- ZDB-FIG-200718-52
- Publication
- Özcan et al., 2020 - Sleep is bi-directionally modified by amyloid beta oligomers
- Other Figures
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- Figure 1
- Figure 1—figure supplement 1.
- Figure 1—figure supplement 2.
- Figure 1—figure supplement 3.
- Figure 2
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(A-B?) Exemplar 24 hr traces comparing the effects of A?long oligomers on average waking activity (A,B) and sleep (A?-B?) versus A?rev on wild type (A,A?), and prp1-/-;prp2-/- mutant (B,B?) backgrounds. (C-D) The effect of A?long relative to A?rev on normalized waking (C) and sleep (D) on wild type and prp1-/-;prp2-/- mutant backgrounds (mixed prp3 background) during the first day is shown. The activity reducing (C) and sleep promoting (D) effects of A?long are blocked in prp1-/-;prp2-/- mutants. **p?0.01, ****p?10?5 one-way ANOVA. Data is pooled from n = 3 independent experiments. See also Figure 4?figure supplements 1 and 2. |
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| Stage: | Day 6 |