FIGURE

Figure 2—figure supplement 1.

ID

ZDB-FIG-200523-33

Publication

Koizumi et al., 2016 - The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction

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Figure 2—figure supplement 1.

The expression and localization of DDI2 were not affected by bortezomib treatment.

(A) Relative mRNA expression of DDI2 in HCT116 cells treated with or without bortezomib (50 nM, 14 hr). The data represent mean + standard error of the mean (SEM) (n = 3, biological replicates). (B) Subcellular localization of DDI2. HEK293A cells stably expressing Venus-Sec61β (ER marker) were transfected with Flag-DDI2 and treated with or without bortezomib.

DOI:http://dx.doi.org/10.7554/eLife.18357.007

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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