FIGURE

FIGURE 7

ID

ZDB-FIG-200306-46

Publication

Idilli et al., 2020 - Expression of tert Prevents ALT in Zebrafish Brain Tumors

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FIGURE 7

Expression of functional tert prolongs survival of fish with brain tumors. (A) Representative fluorescent image of a RAS-Tert brain tumor. Scale bar 0.5 mm. (B) Histological analysis of the RAS-Tert brain tumor shown in panel (A), (C) magnification of two area showing mild neoplastic abnormalities. Scale bars: 20 μm. (D) Immunofluorescence images showing the distribution of the proliferation marker PCNA (magenta) and (E) of the differentiation marker GFAP (magenta) in sections of tumors from RAS-Tert and RAS brains. Scale bar: 20 μm. (F) Survival curve during the entire larval period up to 2 m of Control, RAS and RAS-Tert fish (n = 45–60 larvae/genotype in three independent experiments). See also Supplementary Figure 3.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol