FIGURE

Fig. 1

ID

ZDB-FIG-200203-1

Publication

Wei et al., 2020 - Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo

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Fig. 1

PRL-3 is highly expressed in a majority of human T-ALL.

a Microarray expression analysis of GSE13159 comparing bone marrow samples from healthy donors (n = 72) and T-ALL patients (n = 174), ***p = 6.8e−10. b Analysis of GSE14615 comparing PRL-3 expression between bone marrow samples from T-ALL patients achieving remission and patients with induction failure. NS = not significant. Representative western blot analysis of (c) primary patient T-ALL and PBMCs, and (d) human T-ALL cell lines, showing PRL-3 expression. The total protein loaded in each sample was used as loading control instead of housekeeping protein, with a band of ~50 kD chosen as a representative image in the figure.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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