FIGURE

Fig. 6

ID

ZDB-FIG-200201-15

Publication

Iribarne et al., 2019 - TNFα Induces Müller Glia to Transition From Non-proliferative Gliosis to a Regenerative Response in Mutant Zebrafish Presenting Chronic Photoreceptor Degeneration

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Fig. 6

NPCs express Pax6 during the regenerative response in gosh mutants. Wild-type and gosh mutant retinas labeled with antibodies against Pax6 and GS, which are expressed in NPCs and Müller glia, respectively. In wild-type retinas, Pax6 is observed in amacrine cells and retinal ganglion cells (A,B). Weaker signals were observed in NPCs migrating to the ONL (B, arrowhead). Five-wpf gosh mutant retinas show that Pax6 is expressed in amacrine cells and retinal ganglion cells, as well as probable NPCs migrating toward the ONL (C,D, arrowheads).

Expression Data

Antibodies:	Ab1-glul Ab1-pax6
Fish:	WT aipl2^s341/s341
Anatomical Terms:	amacrine cell Muller cell retinal ganglion cell
Stage:	Days 30-44

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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