FIGURE

Fig 6

ID

ZDB-FIG-191230-767

Publication

Wang et al., 2019 - microRNA-1 Regulates NCC Migration and Differentiation by Targeting sec63

Other Figures

All Figure Page

Back to All Figure Page

Fig 6

Reducing sec63 partly restored the neural crest derivative defects in miR-1 morphants. (A) The defects in melanophores and iridophores were reversed in embryos co-injected with both miR-1 MO and sec63 MO. (B) The craniofacial cartilage were corrected in embryos co-injected with miR-1-MO and sec63-MO. Data are expressed as the mean ± SD, from at least three independent experiments, n=15, **P < 0.01. (C) The expression of dlx2a, ngn1 and crestin were partly rescued at 24 hpf in embryos co-injected with both miR-1 MO and sec63 MO (S1, S2, S3, arrows). (D) The number of ectopic neural crest cells was reduced. microRNA-1, miR-1; morpholino, MO.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Biol. Sci.