ZFIN Image: Wang et al., 2019, Fig 6

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Figure Caption

Fig 6

Reducing sec63 partly restored the neural crest derivative defects in miR-1 morphants. (A) The defects in melanophores and iridophores were reversed in embryos co-injected with both miR-1 MO and sec63 MO. (B) The craniofacial cartilage were corrected in embryos co-injected with miR-1-MO and sec63-MO. Data are expressed as the mean ± SD, from at least three independent experiments, n=15, **P < 0.01. (C) The expression of dlx2a, ngn1 and crestin were partly rescued at 24 hpf in embryos co-injected with both miR-1 MO and sec63 MO (S1, S2, S3, arrows). (D) The number of ectopic neural crest cells was reduced. microRNA-1, miR-1; morpholino, MO.

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