Mathematical description of features calculated from the larval trajectories. (Top) Schematic diagram of the well showing parameters calculated for various features. (Bottom) Table describing the formulae of calculated features for each coordinate of the trajectories. The minimum enclosing ellipsoid with centre (xe, ye) and major and minor axes of a and b is defined as the unique closed ellipse of smallest volume which enclose all points (xi, yi) of a path. is the Euclidean distance of every point of the path to centre of the well (xa, ya). is the distance between the centre of minimum enclosing ellipsoid (xe, ye) and ith point of the path. For each feature, two distinctive numeric examples are provided.
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