FIGURE

Fig. 4.

ID

ZDB-FIG-191230-455

Publication

Chhabria et al., 2019 - Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish

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Fig. 4.

Effect of mannitol/glucose treatmentwith/withoutsodium nitroprusside(SNP) on TRPV4 and glutamine synthetase(GS). (A) Representative micrographs of optic tectum showing the effect of mannitol/glucose treatment with/without SNP treatment on the expression of TRPV4. Scale bars: 20 µm. (B) Quantification of the TRPV4 intensity in the optic tectum in a fixed volume of the tissue (n=21, 20, 24 and 26 larvae for mannitol, mannitol+SNP, glucose and glucose+SNP, respectively). (C) Representative micrographs of optic tectum showing the effect of mannitol/glucose treatment with/without SNP treatment on the expression of GS. Scale bars: 20 µm. (D) Quantification of the GS intensity in the optic tectum in a fixed volume of tissue (n=21, 20, 24 and 26 larvae for mannitol, mannitol+SNP, glucose and glucose+SNP, respectively). Data are mean±s.e.m. *P<0.05, **P<0.01, ****P<0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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