FIGURE

Figure 5

ID

ZDB-FIG-191230-427

Publication

Fernando et al., 2019 - Ishige okamurae Extract and Its Constituent Ishophloroglucin A Attenuated In Vitro and In Vivo High Glucose-Induced Angiogenesis

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Figure 5

(A) IPA suppresses high glucose-induced capillary formation in Matrigel^®. The cells were seeded on Matrigel^® with different concentrations of IPA (0.15, 0.5, and 1.5 µM), along with 30 mM glucose including B (blank (0 mM glucose + 0 µM IPA)) and C (control (30 mM glucose + 0 µM IPA)). After 6 h incubation, the cells were photographed and the angiogenic score was determined. (B) Quantification of capillary formation. The effects of 30 mM glucose on capillary formation were compared to B (blank (0 mM glucose + 0 µM IPA)). The effects of IPA on high glucose-induced capillary formation were normalized to C (control (30 mM glucose + 0 µM IPA)). Scale bar (A) 1000 µm. * p ˂ 0.05, ** p ˂ 0.01, *** p ˂ 0.001, ^###p ˂ 0.001.

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Antibody Labeling

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Acknowledgments

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