FIGURE

Fig. 4

ID

ZDB-FIG-181206-29

Publication

Barrodia et al., 2018 - EF-hand domain containing 2 (Efhc2) is crucial for distal segmentation of pronephros in zebrafish

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Fig. 4

Role of Efhc2 in RA mediated segmentation of pronephros development. a Wild-type embryos or efhc2 morphants were treated with RA. Morphological changes caused by RA treatment in wild-type and efhc2 morphants. WISH showing expression of slc12a1 (DE), slc12a3 (DL) and stc1 (CS). Wild-type embryos or efhc2 morphants were treated with RA (1 × 10⁻⁷ M). efhc2 morphants treated with RA show expansion of expression domain of DE marker slc12a1 and almost or complete loss of DL and CS markers slc12a3 and stc1 as compared with wild-type embryos treated with RA. b Summary of the effects of RA on WT and efhc2 morphants at 48 hpf

Expression Data

Genes:	slc12a1 slc12a3 stc1
Fish:	WT WT + MO1-efhc2
Condition:	chemical treatment by environment: retinoic acid
Knockdown Reagent:	MO1-efhc2
Anatomical Terms:	corpuscles of Stannius pronephric distal early tubule pronephric distal late tubule
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT WT + MO1-efhc2
Condition:	chemical treatment by environment: retinoic acid
Knockdown Reagent:	MO1-efhc2
Observed In:	corpuscles of Stannius pronephric distal early tubule pronephric distal late tubule
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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