ZFIN ID: ZDB-FIG-181011-20
Liu et al., 2018 - Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish. The American journal of pathology   188(4):1043-1058 Full text @ Am. J. Pathol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Long-pec to Day 4
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Long-pec to Day 4

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
DsRed2 hkz04tTg; nz50Tg control Pec-fin caudal hematopoietic tissue neutrophil IFL
hkz04tTg; nz50Tg + MO2-chd7 standard conditions Pec-fin caudal hematopoietic tissue neutrophil IFL
nz50Tg control Protruding-mouth caudal hematopoietic tissue neutrophil IFL
nz50Tg + MO2-chd7 standard conditions Protruding-mouth caudal hematopoietic tissue neutrophil IFL
EGFP hkz04tTg; nz50Tg control Pec-fin caudal hematopoietic tissue lymphoid progenitor cell IFL
Pec-fin caudal hematopoietic tissue macrophage IFL
hkz04tTg; nz50Tg + MO2-chd7 standard conditions Pec-fin caudal hematopoietic tissue lymphoid progenitor cell IFL
Pec-fin caudal hematopoietic tissue macrophage IFL
ikzf1 AB control Long-pec caudal hematopoietic tissue hematopoietic stem cell ISH
Long-pec ventral wall of dorsal aorta hematopoietic stem cell ISH
Long-pec whole organism RTPCR
AB + MO2-chd7 standard conditions Long-pec caudal hematopoietic tissue hematopoietic stem cell ISH
Long-pec ventral wall of dorsal aorta hematopoietic stem cell ISH
Long-pec whole organism RTPCR
irf4a AB control Long-pec caudal hematopoietic tissue pro-T cell ISH
AB + MO2-chd7 standard conditions Long-pec caudal hematopoietic tissue pro-T cell ISH
mfap4 AB control Long-pec whole organism RTPCR
Protruding-mouth caudal hematopoietic tissue macrophage ISH
AB + MO2-chd7 standard conditions Long-pec whole organism RTPCR
Protruding-mouth caudal hematopoietic tissue macrophage ISH
mpx AB control Long-pec whole organism RTPCR
Protruding-mouth caudal hematopoietic tissue neutrophil ISH
AB + MO2-chd7 standard conditions Long-pec whole organism RTPCR
Protruding-mouth caudal hematopoietic tissue neutrophil ISH
myb AB control Long-pec caudal hematopoietic tissue hematopoietic stem cell ISH
Long-pec ventral wall of dorsal aorta hematopoietic stem cell ISH
Long-pec whole organism RTPCR
Day 4 caudal hematopoietic tissue ISH
Day 4 thymus ISH
AB + MO2-chd7 standard conditions Long-pec caudal hematopoietic tissue hematopoietic stem cell ISH
Long-pec ventral wall of dorsal aorta hematopoietic stem cell ISH
Long-pec whole organism RTPCR
Day 4 caudal hematopoietic tissue ISH
Day 4 thymus ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO2-chd7 standard conditions Long-pec caudal hematopoietic tissue hematopoietic stem cell ikzf1 expression increased amount, abnormal
Long-pec caudal hematopoietic tissue hematopoietic stem cell myb expression increased amount, abnormal
Long-pec caudal hematopoietic tissue hematopoietic stem cell increased amount, abnormal
Long-pec caudal hematopoietic tissue pro-T cell increased amount, abnormal
Long-pec caudal hematopoietic tissue pro-T cell irf4a expression increased amount, abnormal
Long-pec thymus primordium lymphoid progenitor cell decreased amount, abnormal
Long-pec ventral wall of dorsal aorta hematopoietic stem cell myb expression increased amount, abnormal
Long-pec ventral wall of dorsal aorta hematopoietic stem cell ikzf1 expression increased amount, abnormal
Long-pec whole organism mpx expression increased amount, abnormal
Long-pec whole organism ikzf1 expression increased amount, abnormal
Long-pec whole organism myb expression increased amount, abnormal
Long-pec whole organism mfap4 expression increased amount, abnormal
Protruding-mouth caudal hematopoietic tissue macrophage increased amount, abnormal
Protruding-mouth caudal hematopoietic tissue macrophage mfap4 expression increased amount, abnormal
Protruding-mouth caudal hematopoietic tissue neutrophil mpx expression increased amount, abnormal
Protruding-mouth caudal hematopoietic tissue neutrophil increased amount, abnormal
Day 4 caudal hematopoietic tissue myb expression increased amount, abnormal
Day 4 caudal hematopoietic tissue hematopoietic stem cell increased amount, abnormal
Day 4 caudal hematopoietic tissue myeloid lineage restricted progenitor cell increased amount, abnormal
Day 4 thymus myb expression decreased amount, abnormal
Day 4 thymus T cell decreased amount, abnormal
hkz04tTg; nz50Tg + MO2-chd7 standard conditions Pec-fin caudal hematopoietic tissue lymphoid progenitor cell EGFP expression increased amount, abnormal
Pec-fin caudal hematopoietic tissue lymphoid progenitor cell increased amount, abnormal
Pec-fin caudal hematopoietic tissue macrophage EGFP expression increased amount, abnormal
Pec-fin caudal hematopoietic tissue macrophage increased amount, abnormal
Pec-fin caudal hematopoietic tissue neutrophil DsRed2 expression increased amount, abnormal
Pec-fin caudal hematopoietic tissue neutrophil increased amount, abnormal
nz50Tg + MO2-chd7 standard conditions Protruding-mouth caudal hematopoietic tissue neutrophil DsRed2 expression increased amount, abnormal
Protruding-mouth caudal hematopoietic tissue neutrophil increased amount, abnormal
Full text @ Am. J. Pathol.