FIGURE

Fig. 10

ID

ZDB-FIG-180620-10

Publication

Gou et al., 2018 - sox2 and sox3 play unique roles in development of hair cells and neurons in the zebrafish inner ear

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Fig. 10

Low-level misexpression of Fgf8 expands sensory potential in the early placode. (A–D) Dorsal views showing expression of pax8 (A, B, anterior up) and atoh1b (C, D, anterior to the left) at 10.8 hpf in control (A, C) and hs:fgf8/+ (B, D) embryos that were heat shocked at 10 hpf, 35 °C for 45 min. (E–G) Quantification of relative surface area of otic/epibranchial pax8 domain (E), atoh1b domain (F) and the number of atoh1b-expressing cells (G) in control and hs:fgf8/+ embryos following heat shock at 10 hpf, 35 °C for 45 min. Error bars represent standard error of the mean. Asterisks indicate statistically significant differences compare to control (*P<0.05, student's t-test, n>22).

Expression Data

Genes:	atoh1b pax8
Fish:	AB x17Tg/+ (AB)
Condition:	heat shock
Anatomical Term:	otic placode
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	x17Tg/+ (AB)
Condition:	heat shock
Observed In:	otic placode
Stage:	1-4 somites

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 435(1), Gou, Y., Vemaraju, S., Sweet, E.M., Kwon, H.J., Riley, B.B., sox2 and sox3 play unique roles in development of hair cells and neurons in the zebrafish inner ear, 73-83, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.