Gene
atoh1b
- ID
- ZDB-GENE-041201-1
- Name
- atonal bHLH transcription factor 1b
- Symbol
- atoh1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have protein dimerization activity and sequence-specific DNA binding activity. Involved in auditory receptor cell fate determination and otolith development. Is expressed in nervous system; otic sensory epithelium; and otic vesicle. Orthologous to human ATOH1 (atonal bHLH transcription factor 1).
- Genome Resources
-
- Alliance (1)
- Gene:493915 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 35 figures from 20 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 89 | Alliance | ?Deafness, autosomal dominant 89 | 620284 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
| Domain | IPR032661 | Transcription factor ATOH1, basic helix-loop-helix domain |
| Family | IPR050359 | Basic helix-loop-helix transcription factors |
| Homologous_superfamily | IPR036638 | Helix-loop-helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Basic helix-loop-helix transcription factors | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Transcription factor ATOH1, basic helix-loop-helix domain |
|---|---|---|---|---|---|
|
UniProtKB:B3DH94
|
206 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance