ZFIN ID: ZDB-GENE-041201-1
Gene Name: atonal bHLH transcription factor 1b
Gene Symbol: atoh1b    Nomenclature History

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Previous Names: Atoh1.2 (1), Zath1b (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Unmapped
Description: Predicted to have protein dimerization activity and sequence-specific DNA binding activity. Involved in auditory receptor cell fate determination and otolith development. Is expressed in nervous system; otic sensory epithelium; and otic vesicle. Orthologous to human ATOH1 (atonal bHLH transcription factor 1).
Genome Resources: Alliance (1),  Gene:493915 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh473 Small Deletion Unknown Unknown CRISPR
sa5874 Point Mutation Unknown Premature Stop ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-atoh1b
1
CRISPR2-atoh1b
1
MO1-atoh1b N/A 8
PHENOTYPE
Data: 2 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH atoh1b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH atoh1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process auditory receptor cell fate determination (more)
Molecular Function protein dimerization activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM atoh1b
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(hsp70l:atoh1b-MYC) hsp70l atoh1b Danio rerio 1 2
MARKER RELATIONSHIPS
atoh1b Encodes: [cDNA] MGC:194100 (1), MGC:194113 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001128679 (1)
Polypeptide UniProtKB:B3DH94 (1) 206 aa
Sequence Information (all 15)
ORTHOLOGY for atoh1b ( Unmapped )
CITATIONS (41)