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ZIRC
ZFIN ID: ZDB-FIG-180522-30
Duong et al., 2017 - Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms. Developmental Biology   434(1):7-14 Full text @ Dev. Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Long-pec

Fig. S2

Generation of second nr2f1a deletion allele. (A) Schematic of deletion in nr2f1a exon 2 induced from the CRISPR/Cas9. (B) Sequence of the 49-bp deletion in the nr2f1aci1009 mutant allele. (C) Schematic indicating the predicted truncation caused by the out of frame deletion. (D,E) WT and nr2f1a ci1009-/- mutant embryos at 48 hpf. Arrow indicates blood pooling and edema on yolk.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
nr2f1aci1009/ci1009 standard conditions Long-pec blood circulation disrupted, abnormal
Long-pec pericardium edematous, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 434(1), Duong, T.B., Ravisankar, P., Song, Y.C., Gafranek, J.T., Rydeen, A.B., Dohn, T.E., Barske, L.A., Crump, J.G., Waxman, J.S., Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms, 7-14, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.