FIGURE

Fig. 7

ID

ZDB-FIG-180420-58

Publication

Raghupathy et al., 2017 - Rpgrip1 is required for rod outer segment development and ciliary protein trafficking in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

Impairment of visual function in rpgrip1 ^?/? zebrafish. (A) Representative ERG traces from wildtype and rpgrip1 ^?/? zebrafish at 7dpf. D-wave was absent in the mutant zebrafish. (B) b-wave amplitudes of rpgrip1 ^?/? zebrafish (n?=?10) were significantly reduced when compared to wildtype siblings (n?=?11). The result is shown as mean?�?SD. SD: standard deviation. **p?<?0.01. (C) Visual background adaption for wildtype (n?=?10) and rpgrip1 ^?/? zebrafish (n?=?10) at 7dpf responding to dark adaption and bright light stimulation. Representative images showing that melanin of wildtype zebrafish was aggregated into small granules after light adaption, while rpgrip1 ^?/? zebrafish displayed larger diffused melanin granules.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	rpgrip1^fh314/fh314
Observed In:	detection of light stimulus involved in visual perception melanocyte melanosome
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.