ZFIN Image: Raghupathy et al., 2017, Fig. 7

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Figure Caption

Fig. 7

Impairment of visual function in rpgrip1 ^−/− zebrafish. (A) Representative ERG traces from wildtype and rpgrip1 ^−/− zebrafish at 7dpf. D-wave was absent in the mutant zebrafish. (B) b-wave amplitudes of rpgrip1 ^−/− zebrafish (n = 10) were significantly reduced when compared to wildtype siblings (n = 11). The result is shown as mean ± SD. SD: standard deviation. **p < 0.01. (C) Visual background adaption for wildtype (n = 10) and rpgrip1 ^−/− zebrafish (n = 10) at 7dpf responding to dark adaption and bright light stimulation. Representative images showing that melanin of wildtype zebrafish was aggregated into small granules after light adaption, while rpgrip1 ^−/− zebrafish displayed larger diffused melanin granules.

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Phenotype details

Acknowledgments

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