FIGURE

Fig. 3

ID

ZDB-FIG-180413-24

Publication

Dunn et al., 2017 - Dual Roles of Fer Kinase Are Required for Proper Hematopoiesis and Vascular Endothelium Organization during Zebrafish Development

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Fig. 3

The loss of Fer kinase function resulted in the loss of early anterior erythrocyte formation and the loss of circulation. o-Dianisidine staining showed the slightly higher levels of erythrocyte heme groups in the posterior trunk region of fer-MO1 embryos at 30 somites (~28 hpf) (C, control-D), but not in the anterior (A), as is observed in control embryos (B). The staining was no longer present in the posterior region at 48 and 72 hpf in fer-MO1 ((E,G) respectively) but regained anterior staining, indicating that later erythrocyte production is functional but no circulation is taking place (control F and H, 48 and 72 hpf respectively).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-fer
Knockdown Reagent:	MO3-fer
Observed In:	blood circulation nucleate erythrocyte trunk nucleate erythrocyte whole organism anterior region whole organism posterior region
Stage Range:	Prim-5 to Protruding-mouth

Phenotype Detail

Acknowledgments

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