FIGURE

Fig. 6

ID
ZDB-FIG-180327-8
Publication
Goodman et al., 2017 - Integrin ?8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells
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Fig. 6

The Itga8?Pcdh15a complex regulates endocytosis/recycling in hair cells. (A?F,H?M) Confocal images of 3?dpf (A?F,H?J) and 5?dpf (K?M) larvae (labeled as in Fig. 1) incubated with FM1-43 for 30?min. Scale bars: 5.5?µm. (G,N) Quantification of total fluorescent intensity per neuromast. At least five independent experiments were performed for each treatment and total fluorescence intensity expressed as a percentage of that in control (mean±s.e.m.). (O) Cartoon of a neuromast (top view) showing the stained structures: hair cells loaded with FM1-43 are in red, and the hair cell bundle in green. **P<0.01; ***P<0.001; ns, not significant (one-way ANOVA followed by Dunnett's multiple comparisons test or two-tailed Student's t-test).
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Protruding-mouth to Day 5

Phenotype Detail
Acknowledgments
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